Best Supplements for Kratom Withdrawal: Evidence-Based Support
schedule9 min readcalendar_todayUpdated Nov 29, 2025
Supportive supplements can reduce withdrawal severity by 30-50% according to community reports. These are not cures but can make the process manageable.
articleMagnesium Glycinate
The #1 supplement for RLS and muscle symptoms.
- Dose: 400-800mg daily (divided AM/PM)
- Why it works: Relaxes muscles, calms nervous system, improves sleep
- Form: Glycinate or threonate (not oxide—poorly absorbed)
- Timing: Start before taper begins
articleVitamin C Megadose Protocol
Widely reported to reduce symptoms 50%+:
- Dose: 5,000-25,000mg daily in divided doses
- Form: Sodium ascorbate (buffered) or liposomal
- Timing: Start at onset of withdrawal, continue through acute phase
- Note: High doses may cause loose stools (bowel tolerance)
articleBlack Seed Oil
Thymoquinone may interact with opioid system:
- Dose: 1-2 teaspoons daily
- Evidence: Community reports of reduced cravings and anxiety
- Form: Cold-pressed oil, not capsules
- Caution: May interact with medications
articleAdaptogens: Ashwagandha & Rhodiola
Ashwagandha:
- Dose: 300-600mg KSM-66 or Sensoril extract
- Benefits: Reduces cortisol, anxiety, supports sleep
- Timing: Evening dose preferred
Rhodiola Rosea:
- Dose: 200-400mg standardized extract
- Benefits: Energy, mental clarity, stress resilience
- Timing: Morning (can be stimulating)
help_outlineFrequently Asked Questions
Magnesium glycinate (400-800mg) is most effective. Hot baths, stretching, and weighted blankets also provide relief.
Many users report significant reduction in symptoms. The mechanism may involve antioxidant support and adrenal function.
menu_bookReferences & Sources
- [1]Magnesium for Sleep and Anxiety(PubMed, 2022)
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